EFFECTIVENESS TEST OF GARLIC ETHANOL EXTRACT ALLIUM SATIVUM IN ACCELERATING WOUND HEALING AFTER TOOTH EXTRACTION

Abstract

One of the various plants in Indonesia that can be developed into traditional medicine is the garlic plant. Garlic has long been known by the public as a plant that has many benefits such as anti-inflammatory, anticancer, antioxidant, antiulcer, and antibacterial. The purpose of this study was to analyse the effectiveness of garlic extract (Allium sativum) for wound healing after tooth extraction. This laboratory experimental study used a complete randomised design with a post-test only control group design pattern. The experimental animals used in this study were 32 male Wistar rats, physically healthy, 2-3 months old, with body weight between 200-250 grams. The rats will be divided into two groups, namely 16 rats treated with 40% garlic extract (Allium sativum) and 16 rats treated with 80% garlic extract (Allium sativum) to see the comparison of accelerated wound healing after tooth extraction. The results showed a significant relationship between the number of fibroblast tissue per visual field in Wistar rats after tooth extraction with the administration of Garlic Extract (Allium sativum) 40% concentration and Garlic Extract (Allium sativum) 80% concentration, p=0.016 (p<0.05). Based on the results and discussion that has been done in this study, it can be concluded that garlic extract (Allium sativum) is effective in accelerating wound healing time after tooth extraction of Wistar rats.