ANALYSIS OF THE EFFECT OF TURMERIC CURCUMA LONGA ETHANOL EXTRACT IN WOUND HEALING AFTER TOOTH EXTRACTION

Abstract

Tooth extraction will cause a wound in the form of exposed alveolar bone in the oral cavity. The wound healing process can be divided into three main phases, namely, the inflammatory phase, the proliferation phase, and the remodeling phase. Curcumin is a bright yellow spice derived from the rhizome of Curcuma longa Linn. Scientific studies have shown the beneficial pharmacological effects of curcumin. This study aims to analyze the impact of administering turmeric (Curcuma longa) extract 35% with 65% in accelerating wound healing time after tooth extraction in Wistar rats. This experimental laboratory study uses a randomized controlled design with a post-test-only control group design pattern, March 2023. The experimental animals used in this study were Wistar rats, 32 males, physically healthy, 2-3 months old, with a body weight between 200-250 grams. There was a significant relationship between the number of fibroblast tissue per field of view in Wistar rats after tooth extraction by administering Turmeric Extract (Curcuma Longa) with a concentration of 35%, and Turmeric Extract (Curcuma Longa) with a concentration of 65%, p = 0.002 (p < 0.05). Conclusion Based on the results and discussions in this study, it can be concluded that turmeric extract (Curcuma Longa) effectively accelerates wound healing time after tooth extraction of Wistar rats. The more sections given increase the effectiveness of healing in the wounds of experimental animals.