IN-VITRO EVALUATION OF DIFFERENT MARKETED BRANDS OF PARACETAMOL TABLETS USING QUALITY CONTROL TESTS

Authors

  • Luhar Shailesh V, Narkhede Sachin B, Lad Harsh H, Patel Shraddha R, Patel Shruti R, Patel Srushti B, Patel Vrutika K, Patel Yukta A Smt. B.N.B Swaminarayan Pharmacy College, National Highway No 48, Shree Swaminarayan Gurukul, Vapi, District Valsad, Gujarat 396191

Keywords:

Paracetamol, Comparative, Quality control parameters, Evaluation

Abstract

Paracetamol is an active ingredient in the antipyretic and pain relievers class. Various brands of certain formulations are available on the market. The primary goal of the study was to compare 500 mg paracetamol tablet brands in vitro. In vitro evaluation guarantees quality, bioavailability and optimal therapeutic activity.

The active metabolite of phenacetin, paracetamol, is widely used for headaches and pains and is one of the main ingredients in many cold and flu remedies.

In the study, 500mg of paracetamol were selected from 5 different manufacturer’s standard tablets. The study was purely experimental and used in vitro testing (IP) and other official literature to evaluate the in vitro quality of paracetamol tablets using various analytical methods and procedures. In the post-evaluation phase, the following post-evaluation parameters were observed: Weight variation, Friability, Hardness, Content uniformity Within the prescribed limit

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How to Cite

Luhar Shailesh V, Narkhede Sachin B, Lad Harsh H, Patel Shraddha R, Patel Shruti R, Patel Srushti B, Patel Vrutika K, Patel Yukta A. (2023). IN-VITRO EVALUATION OF DIFFERENT MARKETED BRANDS OF PARACETAMOL TABLETS USING QUALITY CONTROL TESTS. EPRA International Journal of Research and Development (IJRD), 8(5), 254–258. Retrieved from https://eprajournals.net/index.php/IJRD/article/view/2096

Issue

Vol. 8 No. 5 (2023): EPRA International Journal of Research and Development (IJRD)

Section

Articles