FORMULATION AND EVALUATION OF HERBAL CAPSULE CONTAINING PANEER DODI AND FENUGREEK FOR THE TREATMENT OF DIABETES

Abstract

Withania coagulans is commonly known as Paneer Dodi belonging to family Solanaceae is a well -known plant in herbal medicinal systems having great potential against diabetic disease by improving the secretion of insulin. In addition, Trigonella Foenum Graecum plant is also known as a Methi or fenugreek which is used as ayurvedic medicines for antidiabetic, anti hypercholesterolemic, anti-toxic and immunomodulatory activity. It was though worthwhile to explore its application into our body to treat type-2 diabetes, it acts on the insulin receptors for the better consumption of insulin. The objective of present study was to formulate a dosage form of antidiabetic herbal capsule dosage form having higher efficacy, less side effect and dose accuracy. Our study focuses on preparation of herbal capsule that consist of antidiabetic activity by combination of Paneer Dodi with Fenugreek. The equal proportion of Paneer Dodi and Fenugreek powder (Biherbal powder) is dried & triturate for increase the surface area of powder during dissolution. The Biherbal powder prepared have lack of dose accuracy and bitter taste during consumption thus to overcome this both limitations Powder is filled in Capsule shell which can retain the 300mg of powder. To achieve 1gm dose per day the capsule is given thrice a day. The capsule is disintegrated in 3.5 to 4 minutes and the drug is released and dissolve within a period of 1 hour.